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Prolotherapy is a type of treatment that depends upon the body’s ability to heal itself. In order for the body to heal itself, it needs the active production of collagen. Collagen is the body’s building block. Our body’s tissues are constantly being destroyed and rebuilt. There is a constant need for the production of collagen to keep tissues young looking, young feeling and healthy.

When a person smokes, there is an interference with the production of collagen for at least 30 minutes from the end of the cigarette. If a person smokes one package of cigarettes per day, they are smoking one cigarette every 45 minutes. The collagen production therefore is virtually non-existent on this patient during the 24 hour day. Without collagen, the tissue that is formed does not have normal resistance to injury nor the normal vitality and elasticity that is supposed to be present.

When we do prolotherapy on a patient or in any of our reconstructive type treatments to eliminate pain, we need to avoid and eliminate poisons in the body. Nicotine and other components of cigarette smoke are poisons. They interfere with the autonomic nervous system function and also with the production of collagen tissue. Prolotherapy is not nearly as effective in smokers as one would expect. For someone to go through the inconvenience of getting injected to try to heal his or her body and to smoke at the same time is an absolutely counter productive action on the part of the patient. We therefore, encourage all of our patients to immediately stop smoking and try to do your best to be part of the healing process that you need to rid the pain from your body.


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Alvin Stein, MD. F.A.C.S.
2333 Ponce de Leon Boulevard, Suite 302
Coral Gables, FL 33134
TEL. (954) 581-8585 - FAX305-669-0241

""Poisons and medicine are oftentimes the same substance given with different intents.""

Peter Mere Latham